Meeting attendees are invited to visit the following exhibitors to learn more about the latest techniques and advances in the swiftly evolving world of crystallographic usage and research directly from the manufacturers, suppliers and developers. Visit our exhibitors during the opening reception, morning, lunch and afternoon coffee breaks and poster sessions.

 

AIP Publishing/ACA Structural Dynamics journal

sd.aip.org

 

Co-published by AIP Publishing and ACA, Structural Dynamics is a peer-reviewed, open access, online-only journal that highlights research articles on the structural determination and dynamics of chemical and biological systems and solid materials. Structural Dynamics has received its first impact factor of 3.667!  Stop by our booth to learn more about our upcoming Special Topic Issues and incentives for ACA members.

American Crystallographic Association, Inc.

www.AmerCrytalAssn.org

 

Since 1947, American Crystallographic Assn represents crystallographers in North & South America and welcomes members from around the world. The Canadian Div. exists to promote the interests of Canadian members and provide for an elected official to represent this interest on Council.

There are 12 Scientific Interest Groups: Biological Macromolecules, Fiber Diffraction, General, Industrial, Light Source, Materials Science, Neutron Scattering, Powder Diffraction, Service Crystallography, Small Angle Scattering, Small Molecules, and Young Scientists.

ACA is a Regional Affiliate of IUCr, publishes Structural Dynamics, a online, open access journal, ACA RefleXions, a quarterly magazine, and hosts the largest annual crystallographic annual meeting in the Americas.

 

ACA... where structure matters

American Institute of Physics

www.aip.org

 

Your ACA membership also comes with benefits from AIP, the American Institute of Physics.  AIP has sent Physics Today magazine to ACA members for several decades. AIP also sponsors science policy fellowships for which ACA members can apply, and adds 100+ student members to fuel the future member rolls of ACA.  Come by the booth to learn about other AIP products and services to which you're entitled, including career resources like employment statistics, the Society of Physics Students and an online jobs board.

Anatrace

www.anatrace.com

 

For 30 years, Anatrace has strived to develop and supply the industry's finest products for protein science.  Building on our portfolio of detergents and lipids, the addition of Microlytic crystallization tools and screens and our line of protein purification products, allow us to fully support the entire structural biology pipeline.

Anton Paar

www.anton-paar.com

 

With more than 2000 employees worldwide, Anton Paar provides a dense customer support network. The company offers the most comprehensive range of attachments for non-ambient XRD and is a major supplier of small-angle X-ray equipment worldwide. The SAXSpace system is the most versatile small-and-wide-angle X-ray scattering set-up on the market.

ARINAX

www.arinax.com

 

ARINAX is one of the world leading equipment suppliers for macromolecular X-ray crystallography beamlines. Well known for our single crystal diffractometers MD2 and MD3 we also suggest solutions for the handling of macromolecular crystals. On the ACA2016 and for the first time we'll present our fully automatic crystal harvester CrystalDirect® to the US-American crystallography community. This cutting edge equipment, developed by the European Macromolecular Biology Laboratory (EMBL), will fill an existing gap within the molecular structure determination pipeline, located between crystal growth and structure data collection on synchrotron beamlines.

Art Robbins Instruments

www.artrobbins.com

 

ARI compliments its successful crystallization instrument array with the addition of the CRYSCAM UV,the ultimate detection system for capturing Visual and UV images. The CRYSCAM UV, the CRYSTAL GRYPHON LCP, and the SCOPRION combined with the INTELLI-PLATE® assay plates providespeed, flexibility, accuracy and efficiency in the Crystallization process.

 



Avanti Polar Lipids, Inc.

www.avantilipids.com

 

Avanti Polar Lipids, Inc. has served the Pharmaceutical, Nutraceutical Industries and Lipid Researchers since 1967.
Divisions: Research Products-Highest Purity Lipid Reagents, cGMP Manufacturing-API & Contract Manufacturing, Adjuvants-Immunotherapy & Vaccine Development, Analytical Services-Lipid Analysis, Lipidomics-MS Standards, Antibodies & Lipid Toolbox, Formulations- Liposomes & Nanoparticles, Equipment- Liposome Production Tools, Custom Services-Synthesis & Beyond

BiOptix

www.bioptix.com

 

The BiOptix 404pi Surface Plasmon Resonance (SPR) instrument offers an affordable and powerful solution for drug discovery scientists that require label-free, real-time detection of biomolecular interactions.  BiOptix provides an extremely high sensitivity, low noise instrument at a price point of just $195,000, and offers industry-leading reliability and easy to use software.

Bruker

www.bruker-axs.com

 

Provider of advanced X-ray solutions in life sciences, chemical and materials science. The D8 VENTURE and D8 QUEST solutions for structural biology and chemical crystallography feature the cutting edge PHOTON II CPAD detector. Systems include state of the art rotating anode generators and the new IuS 3.0 microfocus sources with low maintenance and high brilliance for Mo, Ag or Cu. Our industry-leading systems provide highest sensitivity for micro crystals and weak diffractors, with powerful crystallographic software. Stop by booth #25 to see our latest single and dual source systems as well as our revolutionary METALJET Ga X-ray source.

Cambridge Crystallographic Data Centre

www.ccdc.cam.ac.uk

 

The Cambridge Crystallographic Data Centre is dedicated to the advancement of chemistry and crystallography for the public benefit. The CCDC supports structural chemistry research worldwide through the Cambridge Structural Database (CSD), the world's comprehensive, up to date, and fully curated knowledge base of small molecule crystal structures, and research services in collaboration with the world's largest and most experienced team of expert structural chemists' in-house crystallographic expertise, and powerful software solutions.

 

CCP4 - STFC

www.ccp4.ac.uk

 

The Collaborative Computational Project No. 4 (CCP4) provides software for macromolecular structure determination by X-ray crystallography with is widely used by commercial organisations and academic institutions around the world.  CCP4 staff will be available to discuss any aspect of the project, including the latest release (6.5.0), the COOT and CCP4MG molecular graphics packages, and data-processing with MOSFLM and iMOSFLM.  Other highlights in the latest release include refmac5.8 for refinement, CRANK2 for experimental phasing, and core distribution of the ARP/wARP model building package.  Later in the year we will be releasing 7.0 which will include the DIALS data processing software and CCP4i2 (the new CCP4 interface).

CASIS

http://www.iss-casis.org/

 

The mission of the Center for the Advancement of Science in Space (CASIS) is to maximize the utilization of the International Space Station National Laboratory for research and technology development aimed at benefitting humankind. CASIS supports collaboration with NASA, other government agencies, not for profit institutions, industry partners, and commercial entities committed to exploring the intellectual, technological and economic opportunities offered by space.
 
CASIS is actively engaged in supporting projects within the field of protein crystallization.  In addition to supporting current flight projects CASIS is working with the user community to outline the basic science requirements for a long-term protein crystallization program aboard the International Space Station National Lab.  The collaborative initiative is currently outlining the accessibility/timing, resources (flight/ground), education and funding needs required to create a sustainable program.  Ultimately the work will lead to an ISS National Laboratory PCG initiative for repetitive, low-cost crystallization in microgravity providing a platform for human healthcare discovery to users across the discipline including commercial, other government agencies, academia and private research.   In addition to these goals, CASIS is committed to inspiring the next generation through experiential learning opportunities.

 

 

Dectris, Ltd.

www.dectris.com

 

DECTRIS Ltd. is the leading company in Hybrid Photon Counting (HPC) X-ray detection. DECTRIS' pioneering technology has transformed basic research at synchrotron light sources, as well as X-ray applications in laboratory diffractometers. The broad portfolio of DECTRIS' detectors is carefully scaled to meet the needs of various applications. With an aim to continuously improve the measurement quality, DECTRIS also provides solutions for customer developments in scientific and industrial x-ray detection, thereby pushing the state of the art and enabling new scientific findings.

 

 

Douglas Instruments, Ltd.

[email protected]

 

Douglas Instruments designs and manufactures the Oryx range of systems for automatic protein crystallization, offering a variety of screening and optimization techniques and specializing in random microseed matrix-screening (rMMS). Douglas Instruments will be introducing a new technique where rMMS is applied to membrane protein crystallization in LCP. Visit our stand at ACA2016 and see the Oryx4-LCP system in action!
 

Excillum AB

www.excillum.com

 

Excillum makes the world's brightest microfocus x-ray tubes, the MetalJet tubes. The MetalJet x-ray tubes are conventional microfocus tubes with the solid-metal anode replaced by a liquid-metal jet, which is continuously regenerated and already in the molten stage. Thereby, the classical power limit of an x-ray source no longer applies.

FEI Company

www.fei.com

 

FEI is the leading provider of electron microscopes and especially Cryo-Transmission Electron Microscopes (cryo-TEM's), which are used for protein structure determination. In addition to the microscopes themselves we also offer cryo-TEM sample preparation tools, direct electron detectors, and software for automated data acquisition as part of our structural biology workflow.

 

 

Formulatrix

www.formulatrix.com

 

Second Order Non-linear Imaging of Chiral Crystals (SONICC) is an exciting new protein detection tool that uses pulsed lasers to exploit the intrinsic frequency-doubling property found in protein crystals to produce high-contrast images.  Our upgraded UV imaging systems can distinguish between protein and salt crystals with short exposure times and now with improved image quality.  Rock Maker 2.0 is a powerful, yet easy to use software solution that automates the entire protein crystallization process. Formulator is a next-generation liquid handler that uses patent-pending microfluidic technology to dispense reagents up to ten times faster than traditional liquid handlers.

Huber Diffraction/AXO Dresden

www.xhuberusa.com

 

Huber Diffraction designs and manufactures high-precision positioning systems primarily used for X-ray diffraction in laboratories and at synchrotron beam sources. Other application fields are diffraction experiments with neutrons, laser technology, astronomy, and precise measurement technology.

 

www.xhuber.com 

Also representing AXO Dresden, designers and manufacturers of single X-ray optics and complex X-ray optical systems to generate high intensity collimated or focused monochromatic X-ray beams. They offer special customized depositions with applications in X-ray reflectometry and diffraction.

 

International Union of Crystallography

www.iucr.org

 

Visit the IUCr stand to learn more about the exciting developments taking place on our journals and International Tables. Sign up or update your entry in our World Directory of Crystallographers and look out for our Meet-the-Editor-in-Chief reception taking place on Monday 25 July during the afternoon coffee break in Plaza Court Room 2.

IRELEC

www.irelec-alcen.com

 

French engineering company, located in a high-tech environment, IRELEC supplies high reliable robotic systems for Macromolecular Crystallography: automated sample changers for Synchrotron beamlines, automated modules for the CrystalDirect automated crystal harvester by Arinax (EMBL technology), and robotic solutions for home laboratories.www.irelec-alcen.com/en

 

Lawrence Berkeley National Laboratory

www.als.lbl.gov

 

Come to our booth and learn about the ALS scientific program and the outstanding capabilities of its beamlines. You will even have the opportunity to do a test-run on a beamline by remote access! Located above the UC Berkeley campus, the ALS is the destination for over five hundred structural biologists every year, with its world-class beamlines available for protein and chemical crystallography, SAXS on solution samples, and x-ray tomography of whole cells. In addition, chemists, geologists, and materials scientists have performed photo excited-state crystallography, high-pressure experiments mimicking down to the core-mantle boundary, and Laue micro diffraction exploring stress and strain. Many of the MX beamlines have undergone recent optics and endstation upgrades, producing higher flux and smaller spot sizes than ever before. Endstations include advanced features such as user-adjustable variable collimators, outstanding inline sample viewing, high speed detectors, highly automated sample mounting, stream-lined data collection and processing, and remote control capability. The beamline staff are known for their dedication to helping users and their friendly "can-do" attitude.

 

MacCHESS Cornell University

www.macchess.cornell.edu

 

MacCHESS ("Macromolecular diffraction facility at CHESS") is an NIH funded facility at the Cornell High Energy Synchrotron Source. In addition to supporting experiments in macromolecular crystallography and BioSAXS, MacCHESS conducts research in microcrystallography, high pressure cryocooling, BioSAXS development, and macromolecular dynamics. A1, monochromatic beamline, is suitable for general crystallography. The X-ray energy at A1 is currently 19.6 KeV (corresponding to a wavelength of 0.63 Å), due to the use of a diamond monochromator. F1 beamline, with its well-collimated monochromatic beam and Pilatus3 6M pixel array detector, is well suited for large complexes (including viruses). Tuned above the selenium absorption edge, it can also yield excellent SAD data when selenium is present. G1 is a high-flux multilayer BioSAXS station with rock solid beam stability, short exposures and high throughput. Data are automatically collected from two Pilatus detectors simultaneously (SAXS/WAXS), so that merged data cover a q range of 0.006 0.7 Å-1. BioSAXS dedicated chem room is equipped with AKTA Size Exclusion Chromatography, two different spectrophotometers, state-of-the-art multi-angle and dynamic light scattering (MALS/DLS) and refractive index detection (RI). Inline SEC-SAXS-MALS-DLS at the beamline is now available upon request, and has proven to be a powerful tool for resolving difficult aggregation and separation problems. Robotic sample loading is available at both crystallography (F1, A1) and BioSAXS (G1) stations. Microbeam with a focal spot size of 18-20 microns and a 10 fold increase in beam intensity is available at all crystallography beamlines upon request. Users interested in protein crystallography and/or BioSAXS experiments may apply for time using the on-line CHESS application process. Visit https://userdb.chess.cornell.edu.


 

MiTeGen, LLC

www.mitegen.com

 

Because your research is important, we provide tools and solutions that will improve the ease, reproducibility, and quality of your experiments. MiTeGen engineers, manufactures and distributes a full range of the best products for the expression, crystallization, crystal harvesting, and X-ray diffraction data collection for proteins, viruses and small molecule/inorganic compounds

Molecular Dimensions, Inc.

www.moleculardimensions.com

 

Molecular Dimensions founded in 1998 is a world leading supplier of screens, reagents and instrumentation for protein structure determination by X-ray crystallography. As a result of worldwide research collaborations, Molecular Dimensions has introduced over 100 intelligent solutions for: Protein Expression; Crystal growth screening; Custom screens and reagents; Crystal growth plates; Cryocrystallography; Crystal growth storage; Analytical instrumentation. In just one year crystallographers have benefited from new hanging drop kits, UV Microscopes, Bicelle screening, Nucleation analysis, Membrane protein additives, Trace fluorescence, Calixarene additives, Labelling media, Expression optimization, Counter diffusion screening, HT in situ LCP, Nucleic acid screening, Animal product free expression media, LCP screening. Working with crystallographers for crystallographers.

 

Molmex Scientific

www.molmexscientific.com 

 

Molmex Scientific Inc. has been a leader in the field of Small Angle X-ray Scattering (SAXS) for over 2 decades, featuring the Ganesha from SAXSLAB with a moving 2D detector in vacuum. We offer a versatile platform for materials structure analysis including Ultra-SAXS for length scale probes to 5microns, surface structure using Grazing Incidence SAXS and a robotic sampling system for Protein Solution Scattering. We are now distributors of Dynamic and Static Light Scattering instrumentation by industry pioneer LS Instruments from Switzerland. Their products are highlighted by state-of-the-art 3D cross-correlation DLS and Diffusing Wave Spectroscopy (DWS) for Micro-Rheology. 

Oxford Cryosystems, Inc.

www.oxcryo.com

 

Oxford Cryosystems is a market-leading manufacturer of specialist scientific instrumentation and software. The origins of the company lie in the design and manufacture of the original Cryostream Cooler in 1985, which immediately became the system of choice for cooling samples in X-ray diffraction experiments. The range of products for use in sample cooling has now expanded to include liquid-free systems such as our Cobra, helium coolers and specially adapted systems for use with powder diffractometers such as our new liquid-free Chimera with a temperature range of 80- 55 K. Today the company is considered to be the global market leader in X-ray diffraction sample cooling. In addition, our software brand, Crystallographica, offers both free software for crystallography teaching as well as one of the best-known search-match programs, Crystallographica Search Match.

RCSB Protein Data Bank

www.pdb.org & kb.psi-structuralgenomics.org

 

RCSB PDB (rcsb.org) and the PSI Structural Biology Knowledgebase (sbkb.org) are resources for researchers and students studying the biological macromolecules and their relationships to sequence, function, and disease. RCSB PDB provides access to the PDB archive, while the PSI SBKB is a portal to structures, models, methods and more.  Visit to learn about the wwPDB Common Deposition and Annotation System and new tools offered by RCSB PDB.

Rayonix

www.rayonix.com

 

Rayonix, LLC is the leading developer of innovative X-ray detector technologies.The Rayonix frame-transfer CCD, facilitates data collection at up to 140 frames/second. These HS (High-Speed) X-ray detectors have no count rate limitation. New detector designs, including the MX170-HS with a center hole, allow the direct beam to pass through, for simultaneous SAXS/WAXS data collection. Only Rayonix has the technology to bond back-thinned/back-illuminated CCD chips to fiber-optic tapers for the higher electro-optical gain, large-format mosaic HE X-ray detectors. The Rayonix SX165 is widely accepted as the highest quality single-CCD X-ray detector available. Talk to us for custom versions of our detectors for specific needs.


Rigaku/Oxford Diffraction

www.rigaku.com

 

Rigaku Oxford Diffraction combines the expertise of single crystal groups from Rigaku and the former Oxord Diffraction group to provide you with high quality instrumentation and software for X-ray crystallography and small angle X-ray scattering experiments. The goal of this new synergistic organization is to provide tools which drive discoveries and increase our understanding of the universe at a molecular level. Our products include instrumentation and software for chemical crystallography, macromolecular crystallography and biological solution scattering. Additionally, our group includes Rigaku Reagents, which provides reagents and tools for macromoleculer crystallization and cryo-crystallography. Rigaku Oxford Diffraction supports its products with expertly trained engineers and scientists who are dedicated to providing high-quality service through personal accountability and professional commitment to our customers. For more information on Rigaku Oxford Diffraction products, please visit www.rigaku.com.

Southeast Regional CollaborativeAccess Team (SER-CAT)

www.ser-cat.org

 

SER-CAT, a crystallographic research facility at the Advanced Photon Source, Argonne National Laboratory, provides dedicated synchrotron access to an ID and BM beamline for its 21 participating member institutions and 4 associate user groups.  General Users are also accepted by application through the APS. Please visit www.ser-cat.org for additional information.

 

Shamrock Structures is a drug discovery services company that offers research capabilities to pharmaceutical and biotechnology companies.  Shamrock conducts projects in protein crystallography to enable customers to more rapidly discover more potent and selective new drug lead compounds. Since 2003, Shamrock has provided research services including crystallization, co-crystallization, X-ray data collection, structure determination and structure refinement.  We conduct our  X-ray data collection services every week of the year!
 

STOE & Cie gmbH

www.stoe.com


STOE, originally founded in 1887, to manufacture equipment for the optical analysis of crystals, has been a pioneer in powder and single crystal X-ray diffraction since the 1960's, e.g. STOE invented and patented the transmission geometry technique for Powder XRD as well as, for single crystals, produced the first pixel detector XRD system with an open Eulerian cradle. STOE is based in Darmstadt, Germany, and keeps the R&D, software programming, electrical and mechanical engineering and production all in house, allowing STOE to provide customers with standard as well as individual solutions. Whenever it comes to quality, STOE accepts no compromises. This high-level of detail is what sets STOE apart.  STOE is the partner in X-Ray Diffraction to crystallographers, chemists, material scientists and pharmacists all over the world.

TA Instruments

www.tainstruments.com

 

With advanced technology, and unparalleled customer support, TA Instruments is the world leader in microcalorimetry, thermal analysis, and rheology. We offer ultrasensitive, high precision calorimeters for label-free measurements of protein binding and structure. Our new Affinity ITC, the Nano ITC (available in two cell volumes) and our Nano DSC with Autosampler are powerful tools for measuring small-molecule-protein interactions, protein-protein interactions, drug-target binding, and biomolecular structure and stability. The TAM IV isothermal calorimeter is the ultimate platform for isothermal measurements of stability, compatibility, polymorphism, amorphicity and crystallinity, microbial activity, and more. Visit us to learn about the very latest ITC technology, including advanced automation.

 

TTP LabTech, Ltd.

www.ttplabtech.com

 

TTP Labtech's popular mosquito® range offers versatile and robust nanoliter pipetting for protein crystallography irrespective of liquid viscosity. mosquito LCP adds cubic phase dispensing with humidity control for membrane proteins. dragonfly® delivers fast, simple and reproducible optimization of crystallization hit conditions using intuitive licence free software.

XtalConcepts, GmbH

www.xtal-concepts.com/index.php/en/

 

XtalConcepts designs and distributes intruments for nano particle characterization and size determination, particular using in situ dynamic light scattering (DLS) and fluorescence techniques. Our versatile instruments offer various applications in many different sample containers like microfluidics, capillaries, especially designed to investigate biological macromolecules. Nucleation can be detected non-invasively in standard SBS-crystallization plates for optimization of high throughput crystallization.