Job Seekers:  Find available employment positions in crystallography and related disciplins.  Look for jobs based upon location, job description, hiring company.

 

Employers: To post an open position, please download the Job Request Form and email it to aca@hwi.buffalo.edu or fax to (716) 898-8695.  Please be sure to let us know when positions have been filled so we can keep this board as up-to-date as possible.

 

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Browse Job Categories:

Faculty Positions

Industrial and Commercial Positions (permanent)

Other Positions

 

Postdoctoral Job Listings

Postdoc positions are listed separately here.

 

 

 

Faculty & Staff Positions

Date Posted
Job Title Institution Name
Location
12/14/09 Macromolecular X-ray Crystallographer Arizona State University
Tempe, AZ, USA
04/16/10
Structural Biology/Crystallography
University of Waterloo Waterloo ON, Canada
 07/06/10 Research Associate - Bioinformatics
Medical Univ. South Carolina
Charleston, SC, USA
07/21/10
Director, X-ray Crystallography Center
Emory University
Atlanta, GA USA

 

  

 

Industry & Commercial Positions

Date Posted
Job Title Company Name
Location
10/15/09
Scientist/Senior Scientist
Crown Bioscience
Beijing, China
01/21/10 Senior Scientific Software Engineer Rayonix
Evanston, IL, USA
03/26/10
Protein Crystallogrpher
ArQule, Inc.
Wodburn, MA, USA
04/19/10
Senior Director, Structural Biology
Takeda San Diego
San Diego, CA, USA

 

 

 

Other Positions

Date Posted
Job Title Institution Name
Location
No Listings
     

 


 

Faculty Positions

   

Macrocolecular X-Ray Crystallographer

Arizone State University

 

The Department of Chemistry and Biochemistry at ARIZONA STATE UNIVERSITY invites applications for a full-time, state-budgeted position as facilities manager, protein x-ray crystallography and instructional computing resources.

 

A PhD in the chemical sciences or related field and expertise in protein X-ray crystallography are required. Duties include the maintenance and repair of in-house X-ray equipment, management of crystallographic and instructional computing resources, and training of research personnel.

 

Applicants must submit a cover letter, curriculum vitae and summary of research experience as a single electronic PDF document to xraysearch@asu.edu. Applicants must also arrange for three letters of recommendation to be submitted to xraysearch@asu.edu.

 

Cover and recommendations letters should be addressed to:
X-Ray Crystallography Search Committee
Department of Chemistry and Biochemistry
Arizona State University
PO Box 871604
Tempe, AZ 85287-1604

 

For additional information, please contact Dr. Rebekka Wachter at rwachter@asu.edu
Review of applications begins January 25, 2010, and will continue every two weeks thereafter until the position is filled. A background check is required for employment.


ASU is an EO/AA employer and is committed to excellence through diversity. Women and minorities are encouraged to apply.

 

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Structural Biology/Crystallography

Univ of Waterloo


Applications are being accepted for a tenure track position at the Assistant or Associate Professor level in the Department of Biology, Faculty of Science, University of Waterloo. Applicants should have a PhD and postdoctoral experience with a research record in Macromolecular X-ray Crystallography. Duties of the position include establishment of an independent research program, teaching and supervision at the undergraduate and graduate levels, and participation in the running of the Department and University. The University has instrumentation for macromolecular crystallography, including a Rigaku Micromax/R-Axis 4++ diffractometer system.

Inquiries and applications, consisting of a full curriculum vitae with publication record, statement of research interest and teaching experience, and names of three references and their contact information, should be sent electronically to the attention: Dr. David R. Rose, Chair, Department of Biology, University of Waterloo (sent via email to Mrs. Gini Kennings, Chair's Secretary)


The closing date for applications will be September 1, 2010, with a starting date on or after January 1, 2011.

All qualified candidates are encouraged to apply; however Canadian citizens and Permanent residents will be given priority. The University of Waterloo encourages applications from all qualified individuals, including women, members of visible minorities, native peoples, and persons with disabilities.


Contact: 

Mrs. Gini Kennings Chair's Secretary

Dept. of Biology

University of Waterloo

Waterloo, ON N2L 3G1

CANADA

Phone: 519-888-4567 Ext. 33943

Fax: 519-746-0614

Email

 

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Research Associate - Bioinformatics 

Medical Univ. South Carolina 

 

The Medical University of South Carolina (www.musc.edu) seeks a highly motivated individual with expertise in bioinformatics and computational biology to be part of an interdisciplinary core informatics group interacting with a wide range of scientists
addressing basic biomedical questions in genomics, systems biology, and drug discovery.

The candidate should possess a BS, MS or PhD degree in computer science, information sciences, bioinformatics, or computational biology and have demonstrated capabilities in cyber-interface management and enablement, programming, and parallel computing systems related to biomedical-based research. The successful applicant will be part of a rapidly expanding initiative in bioinformatics at MUSC.

Apply on-line at www.jobs.musc.edu (Requisition #046497). Review of applications will begin June 30, 2010. Applications will be accepted until the position is filled and must include a cover letter, resume and at least three references.

Extramural research funding awards to MUSC in fiscal year 2009 exceeded $217 million, reflecting tremendous continued growth in the research enterprise, including most recently a National Cancer Institute (NCI)-designated cancer center, an NIH Clinical and Translational Science Award, and NSF-funded research infrastructure grants that support major regional partnerships across the State of South Carolina. Two new, ~100,000 sq ft research buildings housing programs in Drug Discovery, Cancer Genomics and Bioengineering will open in 2011.

MUSC is located in the beautiful, historic coastal city of Charleston, South Carolina (www.charlestoncvb.com ). Founded in 1824 as the South's first medical school, the Medical University of South Carolina is a publicly supported, free-standing academic
health sciences center composed of six colleges: Dental Medicine, Graduate Studies, Health Professions, Medicine, Nursing, and Pharmacy, as well as the University Hospital Authority. The institution and its affiliates employ approximately 10,000 individuals,
including more than 1,300 faculty members.

Salary is commensurate with experience. MUSC is an equal opportunity employer, supporting workplace diversity.

 

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Director, X-ray Crystallography Center 

Emory University

 

Candidates for the position should have experience in the operation of an X-ray Service Facility as well as considerable experience in X-ray crystallographic techniques and experience in the operation of single crystal and powder diffraction instrumentation including the handling of air sensitive samples. 

 

Start Date:

September 2010

 

Contact: 

Kenneth I. Hardcastle

1515 Dickey Dr

Atlanta, GA 30322

khardca@emory.edu

phone: 404 727 6140

fax: 404 727 6586

 

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Industry Positions

 

Scientist/Senior Scientist - X-Ray Crystallographer in China
Crown Bioscience


Location: Beijing, China
URL: www.crownbio.com
Start Date: as soon as possible
Description: We are seeking highly motivated x-ray crystallographer and protein scientists in our Structural Biology Department at the level of senior Scientist or Scientist depending on qualifications. The successful candidate will be primarily responsible for protein crystallization and structure determination and refinement. The work includes optimization of existing strategies and crystallizing proteins in the presence or absence of small molecule ligands. Experience with protein crystallization, diffraction data collection (in house and synchrotron), structure determination and refinement is required. Experience with high throughput gene-to-structure work including gene cloning, gene expression in different systems (E. coli, baculovirus, and mammalian cells), protein purification are preferred. You are also responsible for writing standard operation procedures, reports and reviews, presenting seminars and interacting with clients regarding work performed, while preparing abstracts, posters, and manuscripts for scientific meetings and publication.


Please submit: CV
Person to contact: Max Wang
Email address: maxwang@crownbio.com
Phone number: +86-10-69719900 ext 501
Job Posted: 10/15/09

 

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Senior Scientific Software Engineer 

Rayonix

 

About the job

We are seeking a Senior Scientific Software Engineer for the design and development of software to support state-of-the-art scientific X-ray detectors. You will be the key contributor in new products and services, using your science background and scientific programming skills. You will be the core contributor in the design and development of software for a major new instrument family, working in close association with Dr. Michael Blum, founder and CEO of Rayonix. In addition, you will work with Dr. Blum and scientists world-wide whose novel research efforts require on-going development and innovation with existing products. You will also manage and mentor other IT-related staff.

 

About the company
Rayonix has an international reputation for providing the most advanced large area X-ray detectors. These instruments are utilized in nearly every major synchrotron across the globe, as well as numerous academic and industrial labs. Our detectors are being used to push forward the frontiers of scientific knowledge in a myriad of different applications, including macromolecular crystallography, small angle X-ray scattering (SAXS), polymers, surface science, and materials science. We have built our reputation on the excellent data quality, solid reliability, ease of use of our instruments, and extraordinary support for our researcher-customers.

 

While our work is quite complex, our work-life is very simple: We are casual, fun, flexible, hard working, and committed to being the very best at what we do.

 

Qualifications:
Candidates considered first for this job will have:

- At least three years of scientific programming using C and C++, Linux/Unix, and more recent applications of object-oriented languages (Python, Perl, etc.)
- Broad product development capability: code architecture, project design, programming, documentation and QA
- Experience with GUI development tools
- Experience with instrument and machine control issues, database structures, and client server applications; experience with scientific instrumentation is preferred
- Excellent written and oral communications
- An advanced degree in physics, engineering, biology, or crystallography would be advantageous
- Experience with scientific instrumentation is desirable; experience with X-ray detectors or other CCD (charge-coupled device) applications even better.

 

Rayonix is most decidedly an equal opportunity employer and qualified candidates with diverse backgrounds are strongly encouraged to apply.

To apply, please go to: http://tinyurl.com/Rayonix-Jobs.

 

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Protein Crystallographer

ArQule, Inc.

 

ArQule has established a cutting-edge kinase discover platform called AKIPTM (ArQule Kinase Inhibitor Discovery) for the discovery of kinase inhibitors that are not classically ATP competitive. ArQule has demonstrated the validity of the approach in its internal discovery portfolio and is also leveraging it to establish research collaborations such as the one with Daiichi Sankyo.

 

This technology utilizes a powerful in silico structure-based drug design approach driven by an in-depth structural biology understanding of the precise mechanism of inhibition of these drug-like molecules.

 

The newly created Structural Biology Group at ArQule is looking to strengthen its team by the addition of a Protein Crystallographer who will be responsible for advancing this new technology by designing and employing a wide variety of biophysical and biochemical methods to extensively study these kinase inhibitors.

 

The suitable candidate will join an experienced and successful multi-disciplinary drug discovery team with a mission to fully develop and utilize this new methodology to bring next-generation kinase inhibitors to the clinic.


Brief Purpose of the job:

Determine structure-function properties of small molecule-protein interactions at ArQule

 

Job Responsibilities:
• Design, expression, purification and characterization of proteins using eukaryotic and microbial expression systems.
• Generate supplies of proteins required for compound target crystallography
• Crystallize, collect x-ray data, solve & refine protein coordinates
• Represent discipline in structure based drug discovery & development teams
• Maintain day-to-day contact with external suppliers of research materials or CROs engaged in supplying custom materials such as cell paste for purification
• Develop and implement protein-ligand interaction assays
• Conduct enzyme kinetics assays

Education: PhD or equivalent in structural biology, biophysics, or related discipline and preferably 2-5 or more years experience in protein X-ray crystallography and structure based drug design in a pharmaceutical or biotechnology environment.

 

Experience:
• Extensive experience in basic molecular cloning techniques including PCR and primer design as well as plasmid purification, and restriction mapping.
• Experience with bioinformatics platform such as DNA and protein sequence analyses, multiple sequence alignments, BLAST, etc.
• Experience in SDS-PAGE including Western-blot analyses.
• Hands-on experience in recombinant protein expression in E. coli, insect cells and mammalian cells.
• Hands-on experience in protein purification using various tag systems and wide range of liquid chromatography methodology.
• Protein crystallization and structure determination by X-ray diffraction.
• Experience in determining protein-ligand interactions and enzyme kinetics

 

Work Habits:

The ideal candidate must be comfortable working in a fast-paced, interdisciplinary environment. He/she must be a team player and has ability to work equally with biologists and chemists. He/she will gain exposure to all aspects of drug discovery and development and must be able to multi-task multiple responsibilities in multiple areas. In addition, written and verbal communication to scientists and non-experts will also be essential for success. The successful candidate will show evidence of sustained productivity and independent contributions in science.

 

Contact: Human Development

ctyre@arqule.com

 

ArQule, Inc.

19 Presidential Way

Woburn, MA 01801

Phone: (781) 994-0330

Fax: (781) 994-0681

 

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Senior Director, Structural Biology

Takeda San Diego

 
Objectives:
Directs, develops and integrates the Company's Structural Biology resources to ensure timely achievement of major goals. Oversees and provides direction for the Molecular Biology, Crystallography, and Protein Chemistry sub-groups. Provides deep expertise and strategic leadership in X-ray crystallography, and across structure based drug design programs in oncology, inflammation and metabolic diseases. Invents and advances drug candidate compounds towards preclinical and clinical development.

Accountabilities
• Directs the management and research activities of TSD Structural Biology departments to enhance the Company's IND success rates, particularly in the oncology, inflammation, and metabolic diseases therapeutic areas..
• Acts as a thought leader in crystallography and structure-based
• Co-leads TSD cross-functional drug discovery programs to achieve compelling target product profiles based on scientific, clinical, regulatory, and commercial rationales
• Plays an integral role in TSD drug discovery target selection and portfolio management both as a member of the TSD Research Committee and in inter-site Takeda forums in the US and Japan.
• Sets annual site-level and multi-year strategic plans, and engages in international corporate strategic planning to fulfill TSD's mission as a Takeda IND engine.
• Directs and controls the activities of one or more functional/technical areas including Molecular Biology, Crystallography, & Protein Chemistry. Responsible for the direct line management of the department team leaders (up to Director level), and for their research and career development
• Effectively communications multiple dimensions of Company's science and business strategies and establishes productive relationships with outside groups, including major collaborations.
• Collaborates with senior management to manage company operations and set company-wide policies
• Budgetary responsibility for functional areas. Summarizes and presents R&D project status, budget, and issues/highlights to senior management and project leaders/teams. Ensures budget requirements are met.
• Teaches, advises, and leads direct and indirect reports in an inspirational fashion, to accomplish key group and corporate objectives

 

Education, Experience, Knowledge And Skills:
• Ph.D. in crystallography, or a related discipline, and a minimum of 12 years industry experience; OR
• MS in chemistry, or related discipline and a minimum of 14 years of industry experience; OR
• BS in chemistry, or related discipline and a minimum of 17 years of industry experience
• Recognized internationally as an expert in crystallography and structure-based drug design
• Track-record of expertise in X-ray crystallography of soluble and membrane-associated proteins and in using crystallographic data to invent potential novel medicines
• Inspirational leadership skills with proven experience in successfully managing large projects and maximizing the performance of large groups of scientists
• Track-record of expertise in structure based drug discovery, including biochemistry, biology, efficacy and Pharmacodynamic/biomarker models, and toxicology
• Extensive knowledge of current drug discovery & development processes worldwide with an emphasis on oncology, inflammation and metabolic disease areas
• Clear record of accomplishment (e.g. publications, patents, presentations) including evidence of leadership in delivering one or more internally discovered compounds into clinical development
• Exceptional interpersonal, collaborative and team-building skills
• Outstanding written and oral communication skills

Physical Demands:
• Potential exposure to hazardous/toxic/dangerous chemicals
• Manual/physical dexterity required to operate basic office equipment (i.e. computers, printers, phones, photocopiers, etc.), and carrying, handling and reaching for objects.
• Prolonged standing and/or sitting.


Travel Requirements:
• Ability to drive or fly to various meetings or client sites, including overnight trips.
• International travel required, including some weekends
• Requires approximately 15 % travel.

Submit your resume and start a quality career with Takeda!

We are an equal opportunity employer.
www.takedasd.com
www.tpna.com

No Phone Calls or Recruiters Please.

 

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