The following is a list of posters by day.  If you are looking for the full text and/or further information regarding the abstract please use our online program to look up abstracts via authors last name.  


ONLINE PROGRAM




 



SATURDAY POSTERS

 

SA1

Structural Characterization of the Helicobacter pylori Peptidyl-Prolyl cis,trans-Isomerase HP0175 Reveals an Extension of Chaperone Helices Upon Target Interaction.   Gerald Audette.

 

SA2

Smyd2 Vs Smyd3: Structure based analysis of small molecule binding selectivity.   Nithya Baburajendran.

 

SA3

Use of polysterism analysis to probe the conformational landscape and residue networks within an a-D-phosphohexomutase.   Lesa Beamer.

 

SA4

A compact, low power infrared tube furnace for in-situ and in-operando X-ray powder diffraction.   Christine Beavers.

 

SA5

Structure of a Green Fluorescent Protein Biosensor - Implications for FRET.   Stefan Becker.

 

SA6

Design and Synthesis of Zwitterionic Metal-Organic Frameworks.  Jenna Brockett.

 

SA7

Bonds, Symmetry and Virtual Atoms.   David Brown.

 

SA8

Solid state structural transformation of two-dimensional coordination polymers.   Robert Burrow.

 

SA10

Discovering Inhibitors of Rumen Methanogens Using High-Throughput X-ray Crystallography and Enzyme Screening Techniques.   Vince Carbone.

 

SA11

Ligand-modulated ring expansion.   VeronicaCarta.

 

SA12

Structural Diversity of Mercury (II) Complexes Derived from Substituted Pyrazoles.   Indranil Chakraborty.

 

SA13

Tetrameric structure of the flagellar cap protein FliD from Serratia marcescens.   SOYEON CHO.

 

SA15

Characterization of the Dual Function of ATXR5 PIP motif in PCNA and Nucleosome Binding.   Hossein Davarinejad.

 

SA16

The Small-Angle X-Ray Scattering Core Facility Of Center For Cancer Research Of National Cancer Institute.   Lixin Fan.

 

SA17

Using topology of molecular solvation to enhance biomolecular structural refinement.   George Giambasu.

 

SA18

Water structure in the intracellular osmosensor WNK1.   El Goldsmith.

 

SA19

Pyridine Complexes of Some First Row Transition Metals.   James Golen.

 

SA20

Resolution of an antifungal compound through co-crystallisation.  Michael Guillot.

 

SA21

Volume-ensemble search models for molecular replacement.   Dmytro Guzenko.

 

SA22

Effects of PKA and CaMKII Phosphorylation on the Ryanodine Receptor Phosphorylation Domain.   Omid Haji-Ghassemi.

 

SA23

Analysis of crystal size and wavelength dependence using the deep UV laser processing crystals.   Ayaka Harada.

 

SA24

Structure Based Drug Design of Clinical Compound MK-8353, a Novel inhibitor of ERK.   Alan Hruza.

 

SA25

Pseudo-Complementary Base-Pairing Involving Sulfur as a Robust Design Element in Crystal Engineering.   Wilhelm Maximilian Hützler.

 

SA26

From X-ray Crystallography to Cryo-Electron Microscopy; Computing Infrastructure in Structural Biology.   Jason Key.

 

SA27

Tracking active-site solvents in human carbonic anhydrase II.   Jin KyunKim.

 

SA28

Nucleation of protein crystals using surface energy modified substrate.   Tiffany Kinnibrugh.

 

SA29

X-Ray mapping in heterocyclic design. X-Ray diffraction study of the derivatives 5-amide-4,6-dimethylpyridone-2.   AnnaKononenko.

 

SA30

Structure-based characterization and optimization of Eph receptor-targeting peptides.   Bernhard Lechtenberg.

 

SA31

Accessing protein conformations of green fluorescent protein NowGFP at cryogenic and room temperature using X-ray crystallography.  Ji-Hye Lee.

 

SA33

Two Energetic Cocrystals of TNT/cyclohexane and picric acid/triethylamine.   Yan Li.

 

SA34

Sample concentration and buffer exchange utilizing a miniaturized tangential flow filtration (TFF) system.   Baker Logan.

 

SA35

Deciphering the role of the Bateman domain in IMPDHs.   Hélène Munier-Lehmann.

 

SA36

Fast Analytical Evaluation of Intermolecular Electrostatic Interaction Energies Using the Pseudoatom Representation of the Electron Density.   Daniel Nguyen.

 

SA37

Arylsulfonyl Derivatives of 11-Azaartemisinin: Approaching New Polymorphs via Seeds of Molecular Analogues.   Madiha Nisar.

 

SA38

Everything Solid-State in Three Weeks: CHEM296 in January Term 2018.   William Ojala.

 

SA39

The time machine: structure-based elucidation of timekeeping mechanisms by the cyanobacterial circadian clock.   Carrie Partch.

 

SA41

Structural insights into the mechanism of ubiquitination by the linear ubiquitin chain assembly complex (LUBAC).   Simin Rahighi.

 

SA42

Structure-guided engineering fine-tunes pharmacokinetics, tolerability, and anti-tumor profile of anti-frizzled antibody.   Swetha Raman.

 

SA43

In-Situ Characterization of the Synthesis of Ca12Al14O33 Under Non-Ambient Atmospheres.   Claudia Rawn.

 

SA44

Sulfur Dioxide-Halide Ion Complexes: A Crystallographic Investigation of Bonding.   Katherine Robertson.

 

SA45

Crystallographic exploration of flexibility in an allosteric enzyme.  David Schuller.

 

SA46

The Role of Tetramethylethylenediamine (TMEDA) in Iron Catalyzed Cross-Coupling Reactions.   Jeffrey Sears.

 

SA48

Acidochromic Spiropyran-Merocyanine stabilisation in the solid state.   Vanessa Kristina Seiler.

 

SA49

Crystalline Products of CO2 Capture by Amines.   VictoriaSena.

 

SA50

Crystal Structure of a Rationally Designed Six-Fold Symmetric DNA Scaffold for the Precise Organization of Biomolecules.   Chad Simmons.

 

SA51

Chiral Segregation of Space by Anionic Assemblies found in Tartramide-based Spiroborate Salts.   Aristyo Soecipto.

 

SA52

Experimental Electron Density Distribution of Tamoxifen Citrate.  Edwin Stevens.

 

SA53

A practical method for an efficient and optimal production of selenomethionine-labeled recombinant protein complexes in the insect cells.   YuichiroTakagi.

 

SA55

Probing the Structure of Axial Water Bound to Copper: An ESEEM Analysis of 17O-Water in Tutton Salt.   JacquelineVitali.

 

SA56

Structure of HIV-1 TAR in Complex with a Lab-Evolved Protein Provides Insight into RNA Recognition and Synthesis of a Constrained Peptide that Impairs Transcription.   Joseph E Wedekind.

 

SA57

Defining the dynamics behind Ryanodine Receptor modulation by small molecules.   Kellie Woll.

 

SA58

Do diverse antifreeze protein structures bind ice by the same mechanism?.   Qilu Ye.

 

SA59

Structural studies of arginine decarboxylase in Helicobacter pylori.   Huawei Zhang.

 

MO138

Using Scipion for Stream Image Processing at CryoEM Facilities.   Jose Miguel de la Rosa Trevin.

 



 


SUNDAY POSTERS

 

SA9

Algebraic search for cooperative-rotational rigid-unit modes.  Branton Campbell.

 

SU60

Purification and characterization of Band 3 complexes from human erythrocyte membranes.   Yazan Abbas.  

 

SU61

Effects of hydration and temperature on side-chain conformational heterogeneity in protein crystals.   Hakan Atakisi.  

 

SU62

Structural insights into biofilm polysaccharide de-N-acetylation in the fungus Aspergillus fumigatus.   Natalie Bamford.  

 

SU63

Investigation of a Novel Slam Dependent Heme Acquisition System in the Bacterial Pathogen Acinetobacter baumannii.   Tom Bateman.  

 

SU64

Crystallisation and Initial Characterization of the periplasmic domain of TraG, the Conjugative Entry Exclusion Protein from the F-plasmid.  Nicholas Bragagnolo.  

 

SU65

Novel protease inhibitors markedly adapting to the structural plasticity of HIV-1 protease exert extreme potency with high genetic barrier.  Haydar Bulut.  

 

SU66

Structural Investigation of a Novel Copper(II) Complex with Pyridoxal Thiosemicarbazone.   Marcio Adriano SousaChagas.  

 

SU67

Structural Analysis of Multiple Lab-Evolved Proteins that Bind HIV-1 TAR RNA with NanoMolar Affinity.   Sai ShashankChavali.  

 

SU68

Structural Determinants for the Activation of Soluble Guanylyl Cyclase.   Kenneth Childers.  

 

SU69

Structural and Functional Analysis of Yeast Shu Complex.   Sam Chu.  

 

SU70

Structural analysis on Salmonella effector SseK3-UDP complex.  Ivy Chung.  

 

SU71

Structure and Function of Terfestatin Biosynthesis Proteins TerB and TerC.   Jonathan Clinger.  

 

SU72

Structural characterization of a novel amino acid decarboxylase.  Raquel Sofia Correia Cordeiro.  

 

SU73

Structural Changes and Control on Conjugation of Glutathione with Chalcones and their Quinolinone Analogues.   JeanCustodio.  

 

SU74

The residues in the hydrophobic core of Staphylococcus aureus Fatty acid Kinase B1 determine fatty acid specificity.   Maxime Cuypers.  

 

SU75

Crystallization of Novel Polyglycine Hydrolases from two fungal families: Epicoccum sorghi and Fusarium solani.   NicoleFraser.  

 

SU76

Structural and functional characterization of bifunctional enzyme encoded by ribBX gene in riboflavin biosynthesis pathway of Helicobacter pylori 26695.   Ruchi Gautam.  

 

SU77

Role of AlgL in Pseudomonas aeruginosa alginate biosynthesis.  Andreea Gheorghita.  

 

SU78

Mechanism of Rad5-mediated DNA rearrangement in error-free template switching.   Melissa Gildenberg.  

 

SU79

Evidence for Breathing of a Class I Fusion Protein at the Cell Surface.   Morgan Gilman.  

 

SU80

A Database Conundrum - MD, SAXS and NMR disorder data.   Garrett Ginell.  

 

SU81

Structural insights into the dimeric human PNPase revealing why the disease-linked mutants exhibit lower RNA import and degradation activities.  Bagher Golzarroshan.  

 

SU82

First experimental visualization of the gaseous product CO2 in the active site of ODCase supports substrate strain as an integral part of the catalytic mechanism.   Ondrej Halgas.  

 

SU83

Supramolecular Effects to Explain a Nonstatistical Disorder.  Joseph Haller.  

 

SU84

2-Hydroxy-3,5-dinitrobenzoate: A Novel μ2-Bridging Ligand.   Jeffrey Haller.  

 

SU85

Structural Studies of Human ATP-Specific Succinyl-CoA Synthetase.  JIHUANG.  

 

SU86

Structural basis for human DNA polymerase kappa to bypass cisplatin intrastrand cross-link (Pt-GG) lesion as an efficient and accurate extender.  VikashJha.  

 

SU87

EM studies of cytochrome bc1 to elucidate inhibitor binding.   Rachel Johnson.  

 

SU88

Structure-guided fusion-protein designs using Bacillus flagellin as a vaccine adjuvant.   meong il Kim.  

 

SU89

Structural insight into degradation mechanism of N-end rule substrates by p62/SQSTM1 selective autophagy adaptor.   Do Hoon Kwon.  

 

SU90

Structural determinants of varying innate immune pathway targeting in YopJ bacterial effectors.   Jonathan Labriola.   

 

SU91

The use of Optical Microscopy and X-ray Powder and Single Crystal Diffraction to Identify and Structurally Characterize Novel Transition Metal Benzoates.   Motunrayo Ladele.  

 

SU92

Substrate specificity of N-methyltransferases in benzylisoquinoline alkaloid metabolism.   Dean Lang.  

 

SU93

Structural and Functional Analysis of a PadR-like Transcription Factor From Bacteroides fragilis.   Choongdeok Lee.  

 

SU94

Pgp2 is an LD-Carboxypeptidase that Determines the Helical Cell Shape of Campylobacter jejuni.   Chang Sheng-HueiLin.  

 

SU95

Cancer-associated mutations of the pre-mRNA splicing factor U2AF2 alter splice site signal recognition.   DebanjanaMaji.  

 

SU96

Crystal structure of arginase from Entamoeba histolytica in complex with substrate analogue inhibitors.   Anjali Malik.  

 

SU97

Effect of pH on Fe-O2 bond in the oxygen reactive hemoglobins of L. pectinata by X-ray Crystallography.   DaryaMarchany-Rivera.  

 

SU98

The molecular mechanism of the type IVa pilus motor.   Matthew McCallum.  

 

SU99

Structural delineation of human antibody responses against malaria transmission-blocking vaccine antigen Pfs25.   Brandon McLeod.  

 

SU100

Optimizing small molecules as a chemical tool to control DNA Repair enzymes using X-ray crystallography and computational techniques.   Davide Moiani.  

 

SU101

Structural investigation of the oligomeric domain of the psychiatric risk protein DISC1.   Anand Nambisan.  

 

SU102

Crystal Structure and Cytotoxic Assay of a Novel Potential Anticancer Chalcone.   Hamilton Napolitano.  

 

SU103

Expression and characterization of Lactase Phlorizin Hydrolase region III.   Nardo Nava.  

 

SU104

Determining the mechanism of LINE-1 ribonucleoprotein particle assembly and inhibition by nucleoside reverse transcriptase inhibitors.   Jocelyn Newton.  

 

SU105

Structural Determination of ATP citrate lyase.   Vinh Nguyen.  

 

SU106

Structural Determinants of LTA4H Aminopeptidase Activation.   SchroederNoble.  

 

SU107

Crystal structure of an As(III) S-adenosylmethionine methyltransferase with both bound ligand and product demonstrates a conformational change in the N- terminal domain during catalysis.   Charles Packianathan.  

 

SU108

Assessment of Structural Features in Cryo-EM Density Maps using SSE and Side Chain Z-Scores.   Greg Pintilie.  

 

SU109

Overexpression, purification of GSK3β and it's interaction with an inhibtory fragment of the psychiatric risk protein DISC1.   NarsimhaPujari.  

 

SU110

Disorder, disulfides and domain-swaps in an oxidized octamer of a gS-crystallin.   Vatsala Sagar.  

 

SU111

Neutron structure and mutagenic analysis of human ABO bloodgroup glycosyltransferases support an orthogonal associative mechanism of stereospecificity.   Brock Schuman.  

 

SU112

Using the 3-D structures of the viral proteinases of Porcine Epidemic Diarrhoea Virus (PEDV) to design anti-PEDV drugs.   Tooba NazShamsi.  

 

SU113

Structural and Functional Studies of E.coli Guanine Deaminase.  Roger Shek.  

 

SU114

Mechanistic underpinnings of allostery, catalysis and domain synchronization in an ammonia tunneling enzyme.   Santosh Shivakumaraswamy.  

 

SU115

Surveillance of the nucleotide pool: Insights into the catalytic mechanism of mycobacterial antimutator protein MutT2.   AmandeepSingh.  

 

SU116

Structural Basis of Conserved Flagellin-mediated TLR5 Stimulation.  WanseokSong.  

 

SU117

DNA Damage Repair - Investigating the Conformations of DNA Ligase and PCNA.   Aleksandr Sverzhinsky.  

 

SU118

Crystallization and structural studies of an aldo-keto reductase from opium poppy.   Miguel Torres.  

 

SU119

Conformational flexibility of pore loop-1 gives insights into substrate translocation by AAA+ protease FtsH.   MatthiasUthoff.  

 

SU120

Diverse ligand-binding domain combinations at the distal end of bacterial RTX adhesins are postal codes for biofilm formation.   Tyler Vance.  

 

SU121

Molecular Mechanisms of AIPL1 and its TPR domain in Leber congenital amaurosis 4 (LCA4) a severe form of childhood blindness.   Ravi PrakashYadav.  

 

SU122

Characterization of C-terminal structure of MinC and its implication in evolution of bacterial cell division.   ShaoyuanYang.  

 

SU123

Cfp1/Cps40 stabilizes MLL complex formation through multi-valent interactions.   Yidai Yang.  

 

SU124

SPOP Oligomerization Drives the Assembly of Multivalent Cullin3-RING Ubiquitin Ligase Complexes.   Darren Yong.  

 

SU125

In-situ measurement of atomic displacement in TiO2 during flash sintering experiments.   Bola Yoon.  

 

SU126

Crystal structure of methylenetetrahydrofolate reductase (MTHFR) from Sphingobium sp. SYK-6.   Hongyang Yu.  

 

SU127

The crystal structure of RTFDC1 reveals a RING-like pseudoheterodimer responsible for pre-mRNA splicing regulation.   Andrew Zhai.  

 

SU128

Self-Assembled Three-Dimensional Deoxyribonucleic Acid (DNA) Crystals.   Yue Zhao.  

 



 

MONDAY POSTERS

 

MO129

Molecular Replacement At SSGCID.   Jan Abendroth.

 

MO130

A micromanufactured dynamic beamstop for continuous measurement of radiation dose.   Marc Allaire.

 

MO132

Recent developments and future of the GM/[email protected] X-ray crystallography user facility at the Advanced Photon Source.   Michael Becker.

 

MO133

Performance without the Pain, Extending the Capabilities of Low-Maintenance Home-Lab Systems for Biological Crystallography.   Matthew Benning.

 

MO134

R&R -a de novo method to create search terms for IUCr documents.   Talapady Bhat.

 

MO135

Ligand binding mode determination in Fragment Based Drug Discovery using X-ray crystallographic data coupled with QM/MM based refinement: Further applications of XModeScore.   Oleg Borbulevych.

 

MO136

Ligand Validation for the Protein Data Bank.   Stephen Burley.

 

MO137

Evaluation of New PHOTON III Detectors for Chemical Crystallography Applications.   Charles Campana.

 

MO139

Molecular Basis Of Cd22 Function And Therapeutic Targeting.   June Ereno Orbea.

 

MO141

Solving structures with native SAD on laboratory X-ray sources.   Andreas Förster.

 

MO142

The Canadian Light Source Annual Mx Data Collection School.   James Gorin.

 

MO143

The MORPHEUS III protein crystallization screen: at the frontier of drug discovery.   Fabrice Gorrec.

 

MO144

Shine Bright Like a Diamond: Microfocus X-ray Sealed Tube Sources with Diamond Hybrid Anode Technology.   Juergen Graf.

 

MO145

IUCr - Supporting Crystallography Around the World.   Marvin Hackert.

 

MO146

BioXTAS RAW: a free open-source program for small-angle X-ray scattering data reduction and analysis.   Jesse Hopkins.

 

MO147

Tau overexpression substantially increase GFAT expression without direct interation.   Zhiqiang Hou.

 

MO148

Microdiffraction Beamline NYX at NSLS-II.   Seetharaman Jayaraman.

 

MO149

A Comparison of Gas Stream and Plunge Cooling in Macromolecular Cryocrystallography.   Douglas Juers.

 

MO150

How new strategies can improve productivity in crystallization and cryoEM.   Stefan Kolek.

 

MO151

Northeastern Collaborative Access Team (NE-CAT) Crystallography Beam Lines for Challenging Structural Biology Research.   Igor Kourinov.

 

MO152

CLS Mail-In Crystallography Highlights.   Shaunivan Labiuk.

 

MO153

The Rigaku Oxford Diffraction XtaLAB Synergy-S, a versatile microfocus sealed tube diffractometer for weakly diffracting samples.   Pierre Le Magueres.

 

MO154

A Low Cost Low-temperature Crystal Mounting Device.   Vincent Lynch.

 

MO156

Structural insights on three series of anti-malarial N-myristoyltransferase inhibitors.   Stephen Mayclin.

 

MO157

Tools and methods to ease the development of scripts for figure making in PyMOL.   Blaine Mooers.

 

MO158

IMCA-CAT Advanced Photon Source Facility for Structure-Based Drug Discovery.   Anne Mulichak.

 

MO159

CMCF-ID: A versatile high-flux and micro-focusing beamline for macromolecular crystallography.   Kiran Mundboth.

 

MO160

Molecular basis for PNAG-dependent biofilm disruption by PgaB.   Roland Pfoh.

 

MO161

Assessment of Structural Features in Cryo-EM Density Maps using SSE and Side Chain Z-Scores (Updated).   Grigore Pintilie.

 

MO162

Structure-based discovery and optimization of inhibitors for the class D β-lactamase OXA-24/40.   Rachel Powers.

 

MO163

An update on detergent usage in Cryo-EM structure determination of membrane proteins.   Edward Pryor.

 

MO164

Dose-sliced data collection; Get the best from that crystal!.   Kanagalaghatta Rajashankar.

 

MO165

Recent Developments at the Beamline for Biological Small Angle X-ray Scattering BL4-2 at SSRL.   Ivan Rajkovic.

 

MO167

Using Modelling and Docking to Search for the Natural Ligand of COUPTFII.   Ross Reynolds.

 

MO168

Announcing the ACA Best Practices for Data Analysis & Archiving Scientific Interest Group.   John Rose.

 

MO169

The Collaborative Crystallography program at the Advanced Light Source.   Banumathi Sankaran.

 

MO170

Structural Basis of Interaction of Herpesvirus Proteins with the Deubiquitinase USP7.   Vivian Saridakis.

 

MO171

Iffy imidazoles: misplaced hydrogen atoms and undetected disorder.   Carl Schwalbe.

 

MO172

Crystallization strategy when no well-diffracted crystals are obtained in the crystallization screening.   Miki Senda.

 

MO173

Structure-based integrated approach for analysis of the GTP metabolism.   Toshiya Senda.

 

MO174

Industrial Macromolecular and Small Molecule Crystallography at the Canadian Light Source.   Denis Spasyuk.

 

MO175

Synthetic glycopeptide selected by directed evolution in complex with anti-HIV-1 Fab 2G12.   Robyn Stanfield.

 

MO177

Impact of Disease-Linked Mutations on the Structure and Activity of Aldehyde Dehydrogenase 7A1 (ALDH7A1).   John Tanner.

 

MO178

Unveiling a Drift Resistant Cryptotope within Marburgvirus Nucleoprotein Recognized by Llama Single-domain Antibodies.   Alex Taylor.

 

MO181

New Developments of X-ray diffraction and pair distribution function beamlines 11-ID and 17-BM at Advanced Photon Source.   Wenqian Xu.

 

MO182

Rcsb Protein Data Bank: Sustaining A Living Digital Data Resource That Enables Breakthroughs In Scientific Research And Biomedical Education.   Christine Zardecki.

 

MO183

DECOR: The Database of Educational Crystallographic Online Resources.   Michael Zdilla.